Science Archives - Horn Creek Hemp The Healing Power of Nature Wed, 07 Aug 2024 11:27:42 +0000 en-US hourly 1 https://horncreekhemp.com/wp-content/uploads/cropped-Horn-Creek-Owl-Logo-black-32x32.png Science Archives - Horn Creek Hemp 32 32 Fall Research On The Farm https://horncreekhemp.com/fall-research-on-the-farm/ https://horncreekhemp.com/fall-research-on-the-farm/#respond Wed, 25 Jan 2023 20:51:31 +0000 https://horncreekhemp.com/?p=54580 From The Jacksonville Review – October 2022 Issue Fall comes on slowly, then all at once. We are approaching that transition. One morning I will be heading to the field, only to turn around to find a coat. And that smell. It must be the world responding to colder temperatures, trees preparing to bear fruit and drop leaves. […]

The post Fall Research On The Farm appeared first on Horn Creek Hemp.

]]>
hemp flower male

Fall Research On The Farm

From The Jacksonville Review – October 2022 Issue

Fall comes on slowly, then all at once. We are approaching that transition. One morning I will be heading to the field, only to turn around to find a coat. And that smell. It must be the world responding to colder temperatures, trees preparing to bear fruit and drop leaves. We all recognize it.

On a brisk-ish morning last week, the OSU Research Center hosted around 75 people from academia,
local government, water districts and Jackson County Building Department. Researchers came from OSU’s Global Hemp Innovation Center, UC Davis and Washington State. Other attendees were from building departments, the USDA and state legislators. They toured our farm, one other in Sam’s Valley, and the OSU experimental hemp grow site. Many had never been to a hemp farm— or at least a legal one.hemp flower up close

The OSU research station has been a tremendous asset to our farm. They are on the forefront of hemp agriculture research, and we are lucky to have them in our fields regularly. They are currently conducting three studies—Common Cannabis pests, diseases, and common pollen. We are pleased to be involved in all three studies. The research they are doing will be used around the country. Hemp farms have been making it up as they go. Careful research upon which to base decisions is something of a novelty.

Our fields are dense and almost ready for harvest. Each flower is stacking up cannabinoids. Hemp and all other cannabis plants are dioecious. This means there are males and females.

We only want female plants, of course because they work harder and are more pleasant. Truthfully, females produce the cannabinoid-rich flower. Males produce pollen, and we do not want pollen near our crop. Pollinated flowers stop producing cannabinoid content to focus on seeds.hemp flower male

Most hemp seed is feminized, which means 99.97% will be female. But sneaky males appear in the field, so we scout for them every day. Males and females look alike until August, when they begin to flower. Just like people, individual plants mature at different times. We’ve spotted them as early as late July, though most show up during August. Males appear
as a subtly different flower structure one day, then they flip seemingly overnight. Daily walks are essential, and they are a bit meditative. It forces one to walk slowly and methodically check each plant. It’s become our evening Zen walk.

hemp flower male plant
Male Hemp Flower Plant

Some plants are undecided. Monoecious, or hermaphrodite plants have both male and female flowers. These appear more frequently in newercultivars, perhaps because they aren’t as stable genetically. Stress makes this more likely. Water deprivation, heat, disease, or poor root systems add stress. One OSU researcher explained a theory in a way I could understand: A plant’s drive is to reproduce. Stress late in the season can prompt an unpollinated plant to react as though it may die without reproducing. The response is to convert a stem or two to male, to self-pollinate and thus extend its genetic line.

Incidental pollination has been a particular problem this year. Last year’s illegal grows were abandoned. Most had volunteer or feral plants this year,half of which are male. I recently walked through an abandoned adjacent field. I stopped counting the males I cut down after 600. This will become a problem in our valley, so the OR Department of Agriculture is looking into rules which will require landowners to remove any volunteer plants on a current or abandoned grow site.

In other news, we’ve been asked to travel to Thailand this fall to assist with the launch of a new farm there. Thailand recently legalized both hemp and marijuana. CBD products in Thailand can only be produced from material grown in-country so they are in a similar green rush as we were several years ago. Thai licenses are restricted somewhat, limiting entrants. In addition, laws are clearer about allowing CBD in food and edible products.

This subtle difference has had a huge impact on how the industry is developing. In the US, grey areas in regulations discouraged big players like Coca-Cola and Frito-Lay from participating. They are waiting until the USDA and FDA make clear rulings. Sidelining these corporations meant that small operations would define and develop the industry. That has been both good and bad. Most important, it has been different from typical product development. It’s been rough at times, but we are grateful for the opportunity.

Thailand is different. Many licenses were obtained by the larger consumer product, distribution and retail entities. They obviously know how to farm quite well. But they don’t have a cannabis background. Believe it or not, Oregon, particularly Southern Oregon, is the elder in the field. It will be fun to help farms bypass the mistakes many of us made.

This hemp venture has been a wild and entertaining ride. Market instability keeps us guessing every day. The Hemp Commission work we’ve been doing is facing a steep decline of farms. It is difficult to make plans when all the pieces are moving simultaneously. We’ve been operating as the temporaryCommission since April. The permanent Commission will be appointed this month. They will have their work cut out for them.

gary west logo

One last development I need to address is how our presence in Jacksonville is changing. Gary West Meats has been operating from Jacksonville since 1966. We are coming up on the end of that era. Gary and Dee West created a world- famous business, focused primarily on delicious smoked steak strips. They were sold around the globe, in Disneyland, Cabela’s, and many other locations. 

In 2003, they turned it over to their daughter, Whitney, and to me. We kept the smokers running until Covid dealt a final and fatal blow. Beef prices doubled. 

Worse was the unstable supply chain for beef. We could not guarantee to our seasonal customers that we would deliver their holiday gifts as requested and on time. So, we made some hard decisions. We ceased production entirely and transitioned to a bottle shop and CBD apothecary. We recently put our building up for sale. When that sale happens, we will maintain a presence in Jacksonville for our farm products.

Share With Friends

The post Fall Research On The Farm appeared first on Horn Creek Hemp.

]]>
https://horncreekhemp.com/fall-research-on-the-farm/feed/ 0
How Is CBDa Different From CBD? https://horncreekhemp.com/cbda-vs-cbd/ https://horncreekhemp.com/cbda-vs-cbd/#comments Sat, 15 Jan 2022 21:58:00 +0000 https://www.horncreekhemp.com/?p=15288 And how is CBGa different from CBG?  The recent COVID study from the Oregon State University’s Global hemp Innovation Center has many asking this question. CBDa vs CBD CBDa is the acidic precursor to CBD. The same is true of CBGa vs CBG. Technically the difference is a few molecular bonds. In practice, the acidic […]

The post How Is CBDa Different From CBD? appeared first on Horn Creek Hemp.

]]>
cbda vs cbd

How Is CBDa Different From CBD?

And how is CBGa different from CBG?  The recent COVID study from the Oregon State University’s Global hemp Innovation Center has many asking this question.

CBDa vs CBD

CBDa is the acidic precursor to CBD. The same is true of CBGa vs CBG. Technically the difference is a few molecular bonds.

In practice, the acidic compounds tend to have more bioavailability. In other words, the mechanism to absorb CBDa and CBGa is more efficient than it is for the non-acidic versions. Anecdotally, CBDa seems to be better for inflammation. CBGa attributes include fighting inflammation. Most interesting is that people report that the presence of CBG and CBGa in a cannabinoid blend enhances the effects of all other cannabinoids. We like to add it to many of our blends for that very reason. We particularly notice a difference in our Dreamland sleep formula. Our Dreamland Tincture will be coming very soon.

Why is CBDa rare?

CBDa is not uncommon. It is the most prevalent cannabinoid in raw hemp flower. But heat converts CBDa to CBD. Most products use concentrates that have converted CBDa to CBD during the extraction process. We are lucky to have a CO2 extractor that is able to control heat and pressure to ensure preservation of 95% or more of the CBDa content. Many CBD formulators believe they must decarboxylate CBDa to CBD. They use heat and time. CBDa and CBGa will convert to their non-acidic counterparts when heated to 240 F for about an hour.

Can I smoke or Vape CBD flower to access CBDa?

No. The act of smoking or vaping heats CBD enough to immediately decarboxylate it. Smoking CBDa and CBGa flower will only result in absorption of CBD and CBG. Both compounds have important and sought-after effects, but they are not the same as those cited in the study that will block the COVID spike protein from absorption into human cells.

Share With Friends

The post How Is CBDa Different From CBD? appeared first on Horn Creek Hemp.

]]>
https://horncreekhemp.com/cbda-vs-cbd/feed/ 2
OSU’s Hemp and SARS-CoV-2 Research https://horncreekhemp.com/osu-hemp-and-covid-study-cbda-cbga-and-horn-creek-hemp/ https://horncreekhemp.com/osu-hemp-and-covid-study-cbda-cbga-and-horn-creek-hemp/#respond Thu, 13 Jan 2022 04:40:00 +0000 https://www.horncreekhemp.com/?p=15259 Do CBDa and CBGa help prevent COVID infection? An interesting study emerging from OSU suggests this is possible. Researchers found that both CBDa and CBGa bind to spike proteins on the virus which blocks a critical step in the infection process. CBGa and CBDa are the acidic precursors to CBD and CBG. It is important […]

The post OSU’s Hemp and SARS-CoV-2 Research appeared first on Horn Creek Hemp.

]]>
osu visiting horn creek's farm

OSU’s Hemp and SARS-CoV-2 Research

Do CBDa and CBGa help prevent COVID infection? An interesting study emerging from OSU suggests this is possible. Researchers found that both CBDa and CBGa bind to spike proteins on the virus which blocks a critical step in the infection process. CBGa and CBDa are the acidic precursors to CBD and CBG. It is important to note that the vast majority of formulated CBD products do not contain the acidic versions. We have specific extraction processes that maintain the acidic versions.

Specifically, our CBDa capsules are made with CO2 extraction techniques to preserve the acid cannabinoid. CBGa is even more challenging to find in formulated products. Our most popular is the concentrated collection of CBGa-rich trichomes. Customers consume this blend raw by adding it to tinctures, oils, or drinks. Our CBG white kief tested at 44% CBGa by weight. 1 gram will contain 440 mg of CBGa!  We have also had feedback from users who are pressing their own CBGa pills and CBGa capsules.

If you wish to make your own CBDa capsules or pills from CBDa oil or kief, there are many home capsule kits for less than $100.  Instructions forthcoming shortly.  Watch this blog for details.

About the study: 

After launching their Global Hemp Innovation Center in 2018, Oregon State University has fast-tracked its research initiatives. Some of these research initiatives include testing Hemp’s Antimicrobial Activity and whether hemp biomass could be used as an animal feed ingredient. On Monday, January 10th, Oregon State’s Richard van Breemen along with Oregon State’s College of Pharmacy, Linus Pauling Institute, and scientists from OSHU published a research paper that demonstrated in vitro that certain cannabinoids block cellular entry of SARS-CoV-2 and the emerging variants. They discovered that two (CBDa & CBGa) cannabinoid acids bind to the SARS-CoV-2 spike protein. This spike protein is the same target that current vaccines and antibodies go after, which shows the potential in disrupting infection and disease progression.

This is not the first time that CBD and other cannabinoids have been used in SARS research, but it could provide insight into why some of the other studies have not been as widely considered successful. A Brazilian study completed in January 2021 showed that a daily administration of 300 mg CBD for 14 days failed to alter the clinical evolution of COVID-19. Israeli research firms Eybna and CannaSoul are teaming up using an NT-VRL compound based on a 2002 SARS study that found terpenes to be effective antiviral agents. They even combined their NT-VRL compound with CBD to find that it was more than twice as effective as just CBD or Dexamethasone (a common corticosteroids treatment for inflammation) in treating cytokine storms.

Utilizing affinity selection mass spectrometry (simply put, incubating the target with a blend of potential ligands or things that might bind to it), Oregon State’s own Richard van Breemen said,

“We identified several cannabinoid ligands and ranked them by affinity to the spike protein. The two cannabinoids with the highest affinities for the spike protein were CBDA and CBGA, and they were confirmed to block infection. These compounds can be taken orally and have a long history of safe use in humans. They have the potential to prevent as well as treat infection by SARS-CoV-2. CBDA and CBGA are produced by the hemp plant as precursors to CBD and CBG, which are familiar to many consumers. However, they are different from the acids and are not contained in hemp products.”

Oregon State’s Richard van Breeman also mentioned that early research showed that licochalcone A, found in Licorice, could also bind to the spike protein, but further research and funding would be needed to test it on a live sample.

Horn Creek is proud to cheer on our friends over at Oregon State in discovering more abstract ways to utilize Hemp. We understand that this is a building block study and not a smoking gun, but local excitement is large and we all love supporting our local community. A tip of our farmer’s cap is deserved, well done.

Share With Friends

The post OSU’s Hemp and SARS-CoV-2 Research appeared first on Horn Creek Hemp.

]]>
https://horncreekhemp.com/osu-hemp-and-covid-study-cbda-cbga-and-horn-creek-hemp/feed/ 0